Combined use of recombinant interlekin-2 and anthelmintic drugs for the treatment of helminthiasis of animals

Relevance. The widespread occurrence of helminthiasis leads to significant economic damage: loss production, decreased fertility, costs for therapeutic and preventive measures, culling mass death domestic animals (especially young animals). Parasitization helminths observed in farm is associated with the development immunodeficiency. Deworming, as a rule, also certain negative changes immune system.Methods. use combination therapy, including anthelmintic drugs recombinant interleukin-2 (Roncoleukin®) treatment various etiologies.Results. anthelmintics pathogenetic therapy promotes restoration immunoreactivity animals, reduces likelihood adverse reactions improves results deworming. cattle, horses pigs increases effectiveness helminthiasis: there decrease intensity invasion by 2, 8, 19 times extent 7, 13, 21%, an increase values 25% extensivity 16, 21%. combined deworming method contributes average daily weight gain comparison monotherapy drugs.